Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Publication Alert

Subtle Alterations in PCNA-Partner Interactions Severely Impair DNA Replication and Repair

Yearit Fridman, Niv Palgi, Daniel Dovrat, Shay Ben-Aroya, Philip Hieter, Amir Aharoni

PLoS Biol 8(10): e1000507
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Publication Alert

Genome-wide model for the normal eukaryotic DNA replication fork

Andres A. Larrea, Scott A. Lujan, Stephanie A. Nick McElhinny, Piotr A. Mieczkowski, Michael A. Resnick, Dmitry A. Gordenin, and Thomas A. Kunkel

PNAS October 12, 2010 vol. 107 no. 41 17674-17679
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Publication Alert

Matthew L. Bochman and Anthony Schwacha

The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'

Nucl. Acids Res. 2010 38: 6078-6088
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Publication Alert

GEMC1 is a novel TopBP1-interacting protein involved in chromosomal DNA replication

Gabriele Piergiovanni and Vincenzo Costanzo

Cell Cycle Volume 9, Issue 18 September 15, 2010 Pages 3662 – 3666
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Publication Alert

Active Site Mutations in Mammalian DNA Polymerase {delta} Alter Accuracy and Replication Fork Progression

Michael W. Schmitt, Ranga N. Venkatesan, Marie-Jeanne Pillaire, Jean-Sebastien Hoffmann, Julia M. Sidorova, and Lawrence A. Loeb

J. Biol. Chem. 2010 285: 32264-32272.
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Publication Alert

Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion

K-M Lau, Q K Y Chan, J C S Pang, K K W Li1, W W Yeung, N Y F Chung, P C Lui, Y-S Tam, H-M Li, L Zhou, Y Wang, Y Mao and H-K Ng

Oncogene (2010) 29, 5475–5489
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Publication Alert

Drosophila Sld5 is essential for normal cell cycle progression and maintenance of genomic integrity

Catherine A. Gougea and Tim W. Christensen

Biochemical and Biophysical Research Communications Volume 400, Issue 1, 10 September 2010, Pages 145-150
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Publication Alert

Molecular architecture of the DNA replication origin activation checkpoint

Slavica Tudzarova, Matthew W B Trotter, Alex Wollenschlaeger, Claire Mulvey, Jasminka Godovac-Zimmermann, Gareth H Williams and Kai Stoeber

The EMBO Journal (2010) 29, 3381 – 3394
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Publication Alert

A multiprotein complex necessary for both transcription and DNA replication at the β-globin locus

Subhradip Karmakar, Milind C Mahajan, Vincent Schulz, Gokul Boyapaty and Sherman M Weissman

The EMBO Journal (2010), 29, 3260 - 3271; 10.1038/emboj.2010.204
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Publication Alert

A WD-Repeat Protein Stabilizes ORC Binding to Chromatin

Zhen Shen, Kizhakke M. Sathyan, Yijie Geng, Ruiping Zheng, Arindam Chakraborty, Brian Freeman, Fei Wang, Kannanganattu V. Prasanth, Supriya G. Prasanth

Molecular Cell, Volume 40, Issue 1, 99-111, 8 October 2010
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Publication Alert

Structural Analysis of the Interactions Between Hsp70 Chaperones and the Yeast DNA Replication Protein Orc4p

María Moreno-del Álamo, Alicia Sánchez-Gorostiaga, Ana M. Serrano, Alicia Prieto, Jorge Cuéllar, Jaime Martín-Benito, José M. Valpuesta and Rafael Giraldo

Journal of Molecular Biology Volume 403, Issue 1, 15 October 2010, Pages 24-39
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