Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen

Bret D. Freudenthal1, John E. Brogie1, Lokesh Gakhar, Christine M. Kondratick and M. Todd Washington

Journal of Molecular Biology Volume 406, Issue 1, 11 February 2011, Pages 9-17
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Publication Alert

Molecular Cooperation between the Werner Syndrome Protein and Replication Protein A in Relation to Replication Fork Blockage

Amrita Machwe, Enerlyn Lozada, Marc S. Wold, Guo-Min Li, and David K. Orren

J. Biol. Chem. 2011 286: 3497-3508.
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Publication Alert

A Dbf4 Mutant Contributes to Bypassing the Rad53-mediated Block of Origins of Replication in Response to Genotoxic Stress

Alba Duch, Gloria Palou, Zophonias O. Jonsson, Roger Palou, Enrique Calvo,James Wohlschlegel, and David G. Quintana

J. Biol. Chem. 2011 286: 2486-2491.
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Publication Alert

Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity

Dorjbal Dorjsuren, Daemyung Kim, David J. Maloney, David M. Wilson, III, and Anton Simeonov

Nucl. Acids Res. 2011 39: e11
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Publication Alert

DNA is a co-factor for its own replication in Xenopus egg extracts

Ronald Lebofsky, Antoine M. van Oijen, and Johannes C. Walter

Nucl. Acids Res. 2011 39: 545-555
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Publication Alert

Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage

Vassilis Roukos, Ali Kinkhabwala, Julien Colombelli, Panagiotis Kotsantis, Stavros Taraviras, Hideo Nishitani, Ernst Stelzer, Philippe Bastiaens and Zoi Lygerou

Journal of Cell Science 124, 422-434 (2011)
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Publication Alert

MCM-BP regulates unloading of the MCM2–7 helicase in late S phase

Atsuya Nishiyama, Lori Frappier, and Marcel Méchali

Genes Dev. January 15, 2011 25: 165-175;
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Publication Alert

Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload

Marjorie A. Kuipers, Timothy J. Stasevich, Takayo Sasaki, Korey A. Wilson, Kristin L. Hazelwood, James G. McNally, Michael W. Davidson, and David M. Gilbert

JCB vol. 192 no. 1 29-41
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Publication Alert

The interacting domains of hCdt1 and hMcm6 involved in the chromatin loading of the MCM complex in human cells

Jingjing Zhang, Lan Yu, Xing Wu, Lan Zou, Kelvin K.L. Sou, Zhun Wei, Xue Cheng, Guang Zhu and Chun Liang

Cell cycle 9, Issue 24 December 15, 2010 Pages 4848 – 4857
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Publication Alert

Replication termination and chromosome dimer resolution in the archaeon Sulfolobus solfataricus

Iain G Duggin, Nelly Dubarry and Stephen D Bell

The EMBO Journal (2011) 30, 145 – 153
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Publication Alert

Proliferating Cell Nuclear Antigen-dependent Rapid Recruitment of Cdt1 and CRL4Cdt2 at DNA-damaged Sites after UV Irradiation in HeLa Cells

Takashi Ishii, Yasushi Shiomi, Toshihiro Takami, Yusuke Murakami, Naho Ohnishi, and Hideo Nishitani

J. Biol. Chem. 2010 285: 41993-42000.
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Publication Alert

An Alternative Pathway for Okazaki Fragment Processing: RESOLUTION OF FOLD-BACK FLAPS BY Pif1 HELICASE

Jason E. Pike, Ryan A. Henry, Peter M. J. Burgers, Judith L. Campbell, and Robert A. Bambara

J. Biol. Chem. 2010 285: 41712-41723.
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Publication Alert

The Transcription Elongation Factor Bur1-Bur2 Interacts with Replication Protein A and Maintains Genome Stability during Replication Stress

Emanuel Clausing, Andreas Mayer, Sittinan Chanarat, Barbara Muller, Susanne M. Germann, Patrick Cramer, Michael Lisby, and Katja Strasser

J. Biol. Chem. 2010 285: 41665-41674.
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Publication Alert

Dbf4 Regulates the Cdc5 Polo-like Kinase through a Distinct Non-canonical Binding Interaction

Ying-Chou Chen and Michael Weinreich

J. Biol. Chem. 2010 285: 41244-41254.
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Publication Alert

Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories

Xin Quan Ge and J. Julian Blow

JCB vol. 191 no. 7 1285-1297
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Publication Alert

Cyclin A Promotes S-Phase Entry via Interaction with the Replication Licensing Factor Mcm7

Taku Chibazakura, Kazuhiro Kamachi, Mayu Ohara, Shoji Tane, Hirofumi Yoshikawa, and James M. Roberts

Molecular and Cellular Biology, January 2011, p. 248-255, Vol. 31, No. 2
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Publication Alert

DNA Replication: Making Two Forks from One Prereplication Complex

Michael Botchan, James Berger

Molecular Cell, Volume 40, Issue 6, 860-861, 22 December 2010

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