Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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The S phase checkpoint promotes the Smc5/6 complex dependent SUMOylation of Pol2, the catalytic subunit of DNA polymerase ε Alicja Winczura, Rowin Appanah, Michael H. Tatham, Ronald T. Hay, Giacomo De Piccoli PLoS Genet 15(11): e1008427
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Sumoylation of the DNA polymerase ε by the Smc5/6 complex contributes to DNA replication Xiangzhou Meng , Lei Wei , Xiao P. Peng, Xiaolan Zhao PLoS Genet 15(11): e1008426
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SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation Ivan Psakhye, Federica Castellucci, Dana Branzei Mol Cell VOLUME 76, ISSUE 4, P632-645.E6
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Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM Thomas C. R. Miller, Julia Locke, Julia F. Greiwe, John F. X. Diffley & Alessandro Costa Nature volume 575, pages704–710(2019)
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BAP1 promotes stalled fork restart and cell survival via INO80 in response to replication stress Han-Sae Lee, Hye-Ran Seo, Shin-Ai Lee, Soohee Choi, Dongmin Kang, Jongbum Kwon Biochem J (2019) 476 (20): 3053-3066.
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DNA Polymerase Delta Synthesizes Both Strands during Break-Induced Replication Roberto A. Donnianni, Xhi-Xiong Zhou, Scott A. Lujan, Amr Al-Zain, Valerie Garcia, Eleanor Glancy, Adam B. Burkholder, Thomas A. Kunkel, Lorraine S. Symington Mol Cell VOLUME 76, ISSUE 3, P371-381.E4
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Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45) Abbey L. Perl, Caitlin M. O'Connor, Pengyan Fa, Franklin Mayca Pozo, Junran Zhang, Youwei Zhang and Goutham Narl The Journal of Biological Chemistry 294, 17043-17059.
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Preparation for DNA replication: the key to a successful S phase Juanita C. Limas Jeanette Gowen Cook febs letters 59 Pages 2853-2867
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The Drosophila melanogaster PIF1 Helicase Promotes Survival During Replication Stress and Processive DNA Synthesis During Double-Strand Gap Repair Ece Kocak, Sarah Dykstra, Alexandra Nemeth, Catherine G. Coughlin, Kasey Rodgers and Mitch McVey GENETICS November 1, 2019 vol. 213 no. 3 835-847; https://www.genetics.org/content/213/3/835
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Checkpoint inhibition of origin firing prevents DNA topological stress Esther C. Morafraile1, Christine Hänni1, George Allen1, Theresa Zeisner, Caroline Clarke, Mark C. Johnson, Miguel M. Santos, Lauren Carroll, Nicola E. Minchell, Jonathan Baxter, Peter Banks, Dave Lydall and Philip Zegerman Genes & Dev. 2019. 33: 1539-1554
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