Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

Pre-Steady State Kinetic Studies of the Fidelity of Nucleotide Incorporation by Yeast DNA Polymerase δ

Lynne M. Dieckman, Robert E. Johnson, Satya Prakash and M. Todd Washington

Biochemistry, 2010, 49 (34), pp 7344–7350
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Publication Alert

Methylated DNA Causes a Physical Block to Replication Forks Independently of Damage Signalling, O6-Methylguanine or DNA Single-Strand Breaks and Results in DNA Damage

Petra Groth, Simon Ausländer, Muntasir Mamun Majumder, Niklas Schultz, Fredrik Johansson, Eva Petermann and Thomas Helleday

Journal of Molecular Biology Volume 402, Issue 1, 10 September 2010, Pages 70-82
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Publication Alert

Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization

Supriya G. Prasantha, Zhen Shen, Kannanganattu V. Prasanth, and Bruce Stillman

PNAS August 24, 2010 vol. 107 no. 34 15093-15098
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Publication Alert

A chromatin-bound kinase, ERK8, protects genomic integrity by inhibiting HDM2-mediated degradation of the DNA clamp PCNA

Angela L. Groehler and Deborah A. Lannigan

JCB vol. 190 no. 4 575-586
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Publication Alert

Replication Termination at Eukaryotic Chromosomes Is Mediated by Top2 and Occurs at Genomic Loci Containing Pausing Elements

Daniele Fachinetti,Rodrigo Bermejo,Andrea Cocito,Simone Minardi,Yuki Katou,Yutaka Kanoh,Katsuhiko Shirahige,Anna Azvolinsky,Virginia A. Zakian, Marco Foiani

Molecular Cell, Volume 39, Issue 4, 595-605, 27 August 2010
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Publication Alert

Loss of DNA Replication Control Is a Potent Inducer of Gene Amplification

Brian M. Green, Kenneth J. Finn, and Joachim J. Li

Science 20 August 2010: 943-946.
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Publication Alert

Regulation of heterochromatic DNA replication by histone H3 lysine 27 methyltransferases

Yannick Jacob, Hume Stroud, Chantal LeBlanc, Suhua Feng, Luting Zhuo, Elena Caro, Christiane Hassel, Crisanto Gutierrez, Scott D. Michaels & Steven E. Jacobsen

Nature 466, 987–991 (19 August 2010)
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Publication Alert

FEN1 Ensures Telomere Stability by Facilitating Replication Fork Re-initiation

Abhishek Saharia, Daniel C. Teasley, Julien P. Duxin, Benjamin Dao, Katherine B. Chiappinelli, and Sheila A. Stewart

J. Biol. Chem. 2010 285: 27057-27066.
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Publication Alert

Homologous Recombination Restarts Blocked Replication Forks at the Expense of Genome Rearrangements by Template Exchange

Sarah Lambert,Ken'ichi Mizuno,Joël Blaisonneau,Sylvain Martineau,Roland Chanet,Karine Fréon,Johanne M. Murray,Antony M. Carr,Giuseppe Baldacci

Molecular Cell, Volume 39, Issue 3, 346-359, 13 August 2010
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Publication Alert

Regulation of DNA Repair through DeSUMOylation and SUMOylation of Replication Protein A Complex

Hong Dou,Chao Huang,Melissa Singh,Phillip B. Carpenter,Edward T.H. Yeh

Molecular Cell, Volume 39, Issue 3, 333-345, 13 August 2010
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