Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in Archaea Mengmeng Sun Xu Feng Zhenzhen Liu Wenyuan Han Yun Xiang Liang Qunxin She Nucleic Acids Research, Volume 46, Issue 13, 27 July 2018, Pages 6697–6711
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An archaeal primase functions as a nanoscale caliper to define primer length Jiangyu Yan, Sandro Holzer, Luca Pellegrini, and Stephen D. Bell PNAS June 26, 2018. 115 (26) 6697-6702
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Conformational control and DNA-binding mechanism of the metazoan origin recognition complex Franziska Bleichert, Alexander Leitner, Ruedi Aebersold, Michael R. Botchan, and James M. Berger PNAS June 26, 2018. 115 (26) E5906-E5915
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Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks Kathrin S Heinz Corella S Casas-Delucchi Timea Török Dusan CmarkoAlexander Rapp Ivan Raska M Cristina Cardoso Nucleic Acids Research, Volume 46, Issue 12, 6 July 2018, Pages 6112–6128,
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Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Jithesh Kottur Deepak T Nair Nucleic Acids Research, Volume 46, Issue 12, 6 July 2018, Pages 5875–5885,
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Structure of the origin recognition complex bound to DNA replication origin Ningning Li, Wai Hei Lam, Yuanliang Zhai, Jiaxuan Cheng, Erchao Cheng, Yongqian Zhao, Ning Gao & Bik-Kwoon Tye Nature volume 559, pages217–222 (2018)
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High speed of fork progression induces DNA replication stress and genomic instability Apolinar Maya-Mendoza, Pavel Moudry, Joanna Maria Merchut-Maya, MyungHee Lee, Robert Strauss & Jiri Bartek Naturevolume 559, pages279–284 (2018)
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Unscheduled DNA synthesis leads to elevated uracil residues at highly transcribed genomic loci in Saccharomyces cerevisiae Norah Owiti, Shanqiao Wei,Ashok S. Bhagwat,Nayun Kim PLoS Genet 14(7): e1007516.
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The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin Sang-Min Jang, Ya Zhang, Koichi Utani, Haiqing Fu, Christophe E. Redon, Anna B. Marks, Owen K. Smith, Catherine J. Redmond, Adrian M. Baris, Danielle A. Tulchinsky & Mirit I. Aladjem Nature Communications volume 9, Article number: 2782 (2018)
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Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells Nozomi Sugimoto Kazumitsu Maehara Kazumasa YoshidaYasuyuki Ohkawa Masatoshi Fujita Nucleic Acids Research, Volume 46, Issue 13, 27 July 2018, Pages 6683–6696,
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