Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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Phosphorylation of Serine 51 Regulates the Interaction of Human DNA Ligase I with Replication Factor C and Its Participation in DNA Replication and Repair Zhimin Peng, Zhongping Liao, Barbara Dziegielewska, Yoshi Matsumoto, Stefani Thomas, Yunhu Wan, Austin Yang, and Alan E. Tomkinson J. Biol. Chem. 2012 287: 36711-36719.
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3D chromatin conformation correlates with replication timing and is conserved in resting cells Benoit Moindrot, Benjamin Audit, Petra Klous, Antoine Baker, Claude Thermes, Wouter de Laat, Philippe Bouvet, Fabien Mongelard, and Alain Arneodo Nucl. Acids Res. 2012 40: 9470-9481
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Geminin Regulates the Transcriptional and Epigenetic Status of Neuronal Fate-Promoting Genes during Mammalian Neurogenesis Dhananjay Yellajoshyula, Jong-won Lim, Dominic M. Thompson Jr, Jacob S. Witt, Ethan S. Patterson and Kristen L. Kroll Mol. Cell. Biol. November 2012 vol. 32 no. 22 4549-4560
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RPA Assists HSF1 Access to Nucleosomal DNA by Recruiting Histone Chaperone FACT Mitsuaki Fujimoto, Eiichi Takaki, Ryosuke Takii, Ke Tan, Ramachandran Prakasam, Naoki Hayashida, Shun-ichiro Iemura, Tohru Natsume, Akira Nakai Molecular Cell, Volume 48, Issue 2, 182-194, 30 August 2012
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Orc2 protects ORCA from ubiquitin-mediated degradation Zhen Shen and Supriya G. Prasanth
Pages Cell cycle 11 3578 – 3589
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Replication timing in a single human chromosome 11 transferred into the Chinese hamster ovary (CHO) cell line Yoshihisa Watanabe, Yasuhiro Kazuki, Mitsuo Oshimura, Toshimichi Ikemura, Masato Maekawa Gene Volume 510, Issue 1, 15 November 2012, Pages 1–6
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DNA Replication Origin Function Is Promoted by H3K4 Di-methylation in Saccharomyces cerevisiae Lindsay F. Rizzardi, Elizabeth S. Dorn, Brian D. Strahl, and Jeanette Gowen Cook Genetics October 2012 192:371-384;
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Impact of Individual Proliferating Cell Nuclear Antigen-DNA Contacts on Clamp Loading and Function on DNA Yayan Zhou and Manju M. Hingorani J. Biol. Chem. 2012 287: 35370-35381.
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The epigenetic control of E-box and Myc-dependent chromatin modificationsregulate the licensing of lamin B2 origin during cell cycle Manickavinayaham Swarnalatha, Anup Kumar Singh, and Vijay Kumar Nucl. Acids Res. 2012 40: 9021-9035 Open Access
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Segregation of Replicative DNA Polymerases during S Phase: DNA POLYMERASE{epsilon}, BUT NOT DNA POLYMERASES {alpha}/{delta}, ARE ASSOCIATED WITH LAMINS THROUGHOUT S PHASE IN HUMAN CELLS Markku Vaara, Harri Itkonen, Tomi Hillukkala, Zhe Liu, Heinz-Peter Nasheuer, Daniel Schaarschmidt, Helmut Pospiech, and Juhani E. Syvaoja J. Biol. Chem. 2012 287: 33327-33338.
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Replication Fork Stalling and Checkpoint Activation by a PKD1 Locus Mirror Repeat Polypurine-Polypyrimidine (Pu-Py) Tract Guoqi Liu, Shere Myers, Xiaomi Chen, John J. Bissler, Richard R. Sinden, and Michael Leffak J. Biol. Chem. 2012 287: 33412-33423.
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Nuclear-to-cytoplasmic Relocalization of the Proliferating Cell Nuclear Antigen (PCNA) during Differentiation Involves a Chromosome Region Maintenance 1 (CRM1)-dependent Export and Is a Prerequisite for PCNA Antiapoptotic Activity in Mature Neutrophils Dikra Bouayad, Magali Pederzoli-Ribeil, Julie Mocek, Celine Candalh, Jean-Benoit Arlet, Olivier Hermine, Nathalie Reuter, Noelie Davezac, and Veronique Witko-Sarsat J. Biol. Chem. 2012 287: 33812-33825.
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The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif Oliver Ohlenschlager, Anja Kuhnert, Annerose Schneider, Sebastian Haumann,Peter Bellstedt, Heidi Keller, Hans-Peter Saluz, Peter Hortschansky, Frank Hanel, Frank Grosse, Matthias Gorlach, and Helmut Pospiech Nucl. Acids Res. 2012 40: 8309-8324
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CHK1 activity is required for continuous replication fork elongation but not stabilization of post-replicative gaps after UV irradiation Ingegerd Elvers, Anna Hagenkort, Fredrik Johansson, Tatjana Djureinovic, Anne Lagerqvist, Niklas Schultz, Ivaylo Stoimenov, Klaus Erixon, and Thomas Helleday Nucl. Acids Res. 2012 40: 8440-8448
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Cyclin-Dependent Kinase Suppression by WEE1 Kinase Protects the Genome through Control of Replication Initiation and Nucleotide Consumption Halfdan Beck, Viola Nähse-Kumpf, Marie Sofie Yoo Larsen, Karen A. O'Hanlon, Sebastian Patzke, Christian Holmberg, Jakob Mejlvang, Anja Groth, Olaf Nielsen, Randi G. Syljuåsen, and Claus Storgaard Sørensen Mol. Cell. Biol. October 2012 32:4226-4236
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