Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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G-quadruplexes Significantly Stimulate Pif1 Helicase-catalyzed Duplex DNA Unwinding Xiao-Lei Duan, Na-Nv Liu, Yan-Tao Yang, Hai-Hong Li, Ming Li, Shuo-Xing Dou and Xu-Guang Xi The Journal of Biological Chemistry, 290, 7722-7735
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Dpb11 Protein Helps Control Assembly of the Cdc45·Mcm2-7·GINS Replication Fork Helicase* Nalini Dhingra, Irina Bruck, Skye Smith, Boting Ning and Daniel L. Kaplan Journal of Biological Chemistry, 290, 7586-7601
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Molecular biology: DNA replication reconstructed Michael Weinreich Nature 519, 418–419 (26 March 2015)
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Regulated eukaryotic DNA replication origin firing with purified proteins Joseph T. P. Yeeles, Tom D. Deegan, Agnieszka Janska, Anne Early & John F. X. Diffley Nature 519, 431–435 (26 March 2015)
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Crystal structure of the eukaryotic origin recognition complex Franziska Bleichert, Michael R. Botchan & James M. Berger Nature 519, 321–326
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DNA Induces Conformational Changes in a Recombinant Human Minichromosome Maintenance Complex Emma L. Hesketh, Richard P. Parker-Manuel, Yuriy Chaban, Rabab Satti, Dawn Coverley, Elena V. Orlova§ and James P. J. Chong Journal of Biological Chemistry, 290, 7973-7979
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H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing Beatrice Rondinelli, Hélène Schwerer, Elena Antonini, Marco Gaviraghi, Alessio Lupi, Michela Frenquelli, Davide Cittaro, Simona Segalla, Jean-Marc Lemaitre, and Giovanni Tonon Nucl. Acids Res. 2015 43: 2560-2574
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Single molecule analysis of Trypanosoma brucei DNA replication dynamics Simone Guedes Calderano, William C. Drosopoulos, Marina Mônaco Quaresma, Catarina A. Marques, Settapong Kosiyatrakul, Richard McCulloch, Carl L. Schildkraut, and Maria Carolina Elias Nucl. Acids Res. 2015 43: 2655-2665
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Replication fork integrity and intra-S phase checkpoint suppress gene amplification Anna Kondratova, Takaaki Watanabe, Michael Marotta, Matthew Cannon, Anca M. Segall, David Serre, and Hisashi Tanaka Nucl. Acids Res. 2015 43: 2678-2690
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High-affinity DNA-binding Domains of Replication Protein A (RPA) Direct SMARCAL1-dependent Replication Fork Remodeling Kamakoti P. Bhat, Rémy Bétous and David Cortez The Journal of Biological Chemistry, 290, 4110-4117.
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Dynamic loading and redistribution of the Mcm2‐7 helicase complex through the cell cycle Sara K Powell, Heather K MacAlpine, Joseph A Prinz, Yulong Li, Jason A Belsky, David M MacAlpine EMBO J Volume 34,12 February 2015 | pp 425 - 577
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Cdc6 Protein Obstructs Apoptosome Assembly and Consequent Cell Death by Forming Stable Complexes with Activated Apaf-1 Molecules Shinichiro Niimi, Shiho Arakawa-Takeuchi, Baasanjav Uranbileg, Jun-ha Park, Shigeki Jinno and Hiroto Okayama The Journal of Biological Chemistry, 287, 18573-18583.
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Lagging-strand replication shapes the mutational landscape of the genome Martin A. M. Reijns, Harriet Kemp, James Ding, Sophie Marion de Procé, Andrew P. Jackson & Martin S. Taylor Nature 518, 502–506 (26 February 2015)
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Crystal Structure of the Human Primase Andrey G. Baranovskiy, Yinbo Zhang, Yoshiaki Suwa, Nigar D. Babayeva, Jianyou Gu, Youri I. Pavlov, and Tahir H. Tahirov J. Biol. Chem. 2015; 290:5635-5646
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A fresh start for stalled forks Mitch Leslie J. Cell Biol. 2015; 208:495
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DNA2 drives processing and restart of reversed replication forks in human cells Saravanabhavan Thangavel, Matteo Berti, Maryna Levikova, Cosimo Pinto, Shivasankari Gomathinayagam, Marko Vujanovic, Ralph Zellweger, Hayley Moore, Eu Han Lee, Eric A. Hendrickson, Petr Cejka, Sheila Stewart, Massimo Lopes, and Alessandro Vindigni J. Cell Biol. 2015; 208:545-562,
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Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells Ralph Zellweger, Damian Dalcher, Karun Mutreja, Matteo Berti, Jonas A. Schmid, Raquel Herrador, Alessandro Vindigni, and Massimo Lopes J. Cell Biol. 2015; 208:563-579
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Error-Free DNA Damage Tolerance and Sister Chromatid Proximity during DNA Replication Rely on the Polα/Primase/Ctf4 Complex Marco Fumasoni, Katharina Zwicky, Fabio Vanoli, Massimo Lopes, Dana Branzei Mol cell Volume 57, Issue 5, p812–823, 5 March 2015
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Switch on the engine: how the eukaryotic replicative helicase MCM2–7 becomes activated Silvia Tognetti, Alberto Riera, Christian Speck Chromosoma March 2015, Volume 124, Issue 1, pp 13-26Pages 13-26
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DNA replication in nurse cell polytene chromosomes of Drosophila melanogaster otu mutants Dmitry E. Koryakov ad Igor F. Zhimulev Chromosoma March 2015, Volume 124, Issue 1, pp 95-106
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Replication protein A prevents promiscuous annealing between short sequence homologies: Implications for genome integrity Sarah K. Deng, Huan Chen and Lorraine S. Symington BioEssays Volume 37, Issue 3, pages 305–313, March 2015
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Ribonucleotides in DNA: hidden in plain sight Sue Jinks-Robertson & Hannah L Klein Nature Structural & Molecular Biology 22, 176–178 (2015)
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Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation Anders R Clausen, Scott A Lujan, Adam B Burkholder, Clinton D Orebaugh, Jessica S Williams, Maryam F Clausen, Ewa P Malc, Piotr A Mieczkowski, David C Fargo, Duncan J Smith & Thomas A Kunkel Nature Structural & Molecular Biology 22, 185–191 (2015)
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A global profile of replicative polymerase usage - Yasukazu Daigaku, Andrea Keszthelyi, Carolin A Müller, Izumi Miyabe, Tony Brooks, Renata Retkute, Mike Hubank, Conrad A Nieduszynski & Antony M Carr Nature Structural & Molecular Biology 22, 192–198 (2015)
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