Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

Cdc6 Stability Is Regulated by the Huwe1 Ubiquitin Ligase after DNA Damage

Jonathan R. Hall, Evelyn Kow, Kathleen R. Nevis, Chiajung Karen Lu, K. Scott Luce, Qing Zhong, and Jeanette Gowen Cook

MBC Vol. 18, Issue 9, 3340-3350, September 2007
Comments

Publication Alert

The Mre11 Complex Mediates the S-Phase Checkpoint through an Interaction with Replication Protein A

Erin Olson, Christian J. Nievera, Enbo Liu,Alan Yueh-Luen Lee, Longchuan Chen and Xiaohua Wu

Molecular and Cellular Biology, September 2007, p. 6053-6067, Vol. 27, No. 17
Comments

Publication Alert

DNA Replication Stress Is a Determinant of Chronological Lifespan in Budding Yeast

Martin Weinberger, Li Feng, Anita Paul, Daniel L. Smith, Jr., Robert D. Hontz, Jeffrey S. Smith, Marija Vujcic, Keshav K. Singh, Joel A. Huberman, William C. Burhans

PLoS ONE 2(8): e748.
Comments

Publication Alert

Reducing DNA Polymerase in the Absence of Drosophila ATR Leads to P53-Dependent Apoptosis and Developmental Defects

Jeannine R. LaRocque, Diana L. Dougherty, Sumreen K. Hussain and Jeff Sekelsky

Genetics 176: 1441–1451 ( July 2007)
Comments

Publication Alert

Global Profiling of DNA Replication Timing and Efficiency Reveals that Efficient Replication/Firing Occurs Late during S-Phase in S. pombe

Majid Eshaghi, R. Krishna M. Karuturi, Juntao Li, Zhaoqing Chu, Edison T. Liu, Jianhua Liu

PLoS ONE 2(8): e722.
Comments

Publication Alert

Human INT6 interacts with MCM7 and regulates its stability during
S phase of the cell cycle


S Buchsbaum, C Morris, V Bochard and P Jalinot

Oncogene (2007) 26, 5132–5144
Comments

Publication Alert

Top1- and Top2-mediated topological transitions at replication forks ensure fork progression and stability and prevent DNA damage checkpoint activation

Rodrigo Bermejo, Ylli Doksani, Thelma Capra, Yuki-Mori Katou, Hirokazu Tanaka, Katsuhiko Shirahige, and Marco Foiani

GENES & DEVELOPMENT 21:1921-1936, 2007
Comments

Publication Alert

The Intra-S-Phase Checkpoint Affects both DNA Replication Initiation and Elongation: Single-Cell and -DNA Fiber Analyses

Jennifer A. Seiler, Chiara Conti, Ali Syed, Mirit I. Aladjem, and Yves Pommier

Molecular and Cellular Biology, August 2007, p. 5806-5818, Vol. 27, No. 16
Comments

Publication Alert

High-throughput mapping of origins of replication in human cells

Isabelle Lucas, Aparna Palakodeti, Yanwen Jiang, David J Young, Nan Jiang, Anthony A Fernald & Michelle M Le Beau

EMBO reports 8, 8, 770–777 (2007)
Comments

Publication Alert

Crystal structure of the GINS complex and functional
insights into its role in DNA replication


Y. Paul Chang, Ganggang Wang, Vladimir Bermudez, Jerard Hurwitz, and Xiaojiang S. Chen


PNAS July 31, 2007 vol. 104 12685-12690
Comments

Publication Alert

Non-transcriptional control of DNA replication by c-Myc

David Dominguez-Sola, Carol Y. Ying, Carla Grandori, Luca Ruggiero, Brenden Chen, Muyang Li, Denise A. Galloway, Wei Gu, Jean Gautier & Riccardo Dalla-Favera

Nature 448, 445-451 (26 July 2007)
Comments

Publication Alert

Yeast DNA Polymerase Participates in Leading-Strand DNA Replication

Zachary F. Pursell, Isabelle Isoz, Else-Britt Lundström, Erik Johansson, Thomas A. Kunkel

Science 6 July 2007: Vol. 317. no. 5834, pp. 127 - 130
Comments