Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

Rif1 is a global regulator of timing of replication origin firing in fission yeast

Motoshi Hayano, Yutaka Kanoh, Seiji Matsumoto, Claire Renard-Guillet, Katsuhiko Shirahige, and Hisao Masai

Genes Dev. January 15, 2012 26: 137-150
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Publication Alert

A Central Swivel Point in the RFC Clamp Loader Controls PCNA Opening and Loading on DNA

Miho Sakato, Mike O'Donnell, Manju M. Hingorani

Journal of Molecular Biology, Volume 416, Issue 2, 17 February 2012, Pages 163–175
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Publication Alert

The dynamics of replication licensing in live Caenorhabditis elegans embryos

Remi Sonneville, Matthieu Querenet, Ashley Craig, Anton Gartner, and J. Julian Blow

JCB vol. 196 no. 2 233-246
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Publication Alert

Forkhead Transcription Factors Establish Origin Timing and Long-Range Clustering in S. cerevisiae

Simon R.V. Knott,Jared M. Peace,A. Zachary Ostrow,Yan Gan,Alexandra E. Rex,Christopher J. Viggiani,Simon Tavaré,Oscar M. Aparicio

Cell, Volume 148, Issue 1, 99-111, 20 January 2012
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Publication Alert

Replication Factor C Is a More Effective Proliferating Cell Nuclear Antigen (PCNA) Opener than the Checkpoint Clamp Loader, Rad24-RFC

Jennifer A. Thompson, Melissa R. Marzahn, Mike O'Donnell, and Linda B. Bloom

J. Biol. Chem. 2012 287: 2203-2209.
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Publication Alert

Origin Association of Sld3, Sld7, and Cdc45 Proteins Is a Key Step for Determination of Origin-Firing Timing

Seiji Tanaka, Ryuichiro Nakato, Yuki Katou, Katsuhiko Shirahige, Hiroyuki Araki

Current Biology, Volume 21, Issue 24, 2055-2063,
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Publication Alert

RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks

Yoshitami Hashimoto, Fabio Puddu & Vincenzo Costanzo

Nature Structural & Molecular Biology 19, 17–24 (2012)
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Publication Alert

Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin

Corella S. Casas-Delucchi, Joke G. van Bemme, Sebastian Haase, Henry D. Herce, Danny Nowak, Daniela Meilinger, Jeffrey H. Stear, Heinrich Leonhardt and M. Cristina Cardoso

Nucl. Acids Res. (2012) 40 (1): 159-169
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Publication Alert

Nucleosomal organization of replication origins and meiotic recombination hotspots in fission yeast

Elisa de Castro, Ignacio Soriano, Laura Marín, Rebeca Serrano, Luis Quintales and Francisco Antequera

The EMBO Journal (2012) 31, 124 - 137
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Publication Alert

Phosphorylation of the p68 Subunit of Pol δ Acts as a Molecular Switch To Regulate Its Interaction with PCNA

Amal A. Rahmeh, Yajing Zhou, Bin Xie, Hao Li, Ernest Y. C. Lee, and Marietta Y. W. T. Lee

Biochemistry, 2012, 51 (1), pp 416–424
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Publication Alert

RECQL4, the Protein Mutated in Rothmund-Thomson Syndrome, Functions in Telomere Maintenance

Avik K. Ghosh, Marie L. Rossi, Dharmendra Kumar Singh, Christopher Dunn, Mahesh Ramamoorthy, Deborah L. Croteau, Yie Liu, and Vilhelm A. Bohr

J. Biol. Chem. 2012 287: 196-209.
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Publication Alert

Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins

Maria Sideridou, Roubini Zakopoulou, Konstantinos Evangelou, Michalis Liontos, Athanassios Kotsinas, Emmanouil Rampakakis, Sarantis Gagos, Kaoru Kahata, Kristina Grabusic, Kalliopi Gkouskou, Ioannis P. Trougakos1, Evangelos Kolettas, Alexandros G. Georgakilas, Sinisa Volarevic, Aristides G. Eliopoulos, Maria Zannis-Hadjopoulos, Aristidis Moustakas, and Vassilis G. Gorgoulis

JCB vol. 195 no. 7 1123-1140
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Publication Alert

Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin

Corella S. Casas-Delucchi, Joke G. van Bemmel, Sebastian Haase, Henry D. Herce, Danny Nowak, Daniela Meilinger, Jeffrey H. Stear, Heinrich Leonhardt, and M. Cristina Cardoso

Nucl. Acids Res. 2012 40: 159-169
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Publication Alert

The RecQ4 Orthologue Hrq1 Is Critical for DNA Interstrand Cross-Link Repair and Genome Stability in Fission Yeast

Lynda M. Groococka, John Pruddena, J. Jefferson P. Perrya,b and Michael N. Boddy

Mol. Cell. Biol. January 2012 vol. 32 no. 2
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Publication Alert

Cdc7-Dbf4 Is a Gene-Specific Regulator of Meiotic Transcription in Yeast

Hsiao-Chi Lo, Ryan C. Kunz, Xiangyu Chen, Allison Marullo, Steven P. Gygi, and Nancy M. Hollingsworth

Mol. Cell. Biol. January 2012 32:541-557
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Publication Alert

Analysis of model replication origins in Drosophila reveals new aspects of the chromatin landscape and its relationship to origin activity and the prereplicative complex

Jun Liu, Kristopher McConnell, Michael Dixon, and Brian R. Calvi

Mol. Biol. Cell 2012 23:1 200-212;
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