Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

22-Nov-2007 09:40 | Permalink
Structure of the Full-length Human RPA14/32 Complex Gives Insights into the Mechanism of DNA Binding and Complex Formation

Xiaoyi Deng, Jeff E. Habel, Venkataramen Kabaleeswaran, Edward H. Snell, Marc S. Wold and Gloria E.O. Borgstahl

Journal of Molecular Biology Volume 374, Issue 4, 7 December 2007, Pages 865-876
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Publication Alert

22-Nov-2007 09:38 | Permalink
MCM Forked Substrate Specificity Involves Dynamic Interaction with the 5'-Tail

Eli Rothenberg, Michael A. Trakselis, Stephen D. Bell, and Taekjip Ha,

J. Biol. Chem., Vol. 282, Issue 47, 34229-34234, November 23, 2007
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Publication Alert

22-Nov-2007 09:37 | Permalink
Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication

Priya Aggarwal, Matthew D. Lessie, Douglas I. Lin, Laura Pontano, Andrew B. Gladden, Beth Nuskey, Ami Goradia, Mariusz A. Wasik, Andres J.P. Klein-Szanto, Anil K. Rustgi, Craig H. Bassing, and J. Alan Diehl

GENES & DEVELOPMENT 21:2908-2922, 2007
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Publication Alert

22-Nov-2007 09:36 | Permalink
Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2–7 loading

Shuyan Chen, Milan A. de Vries, and Stephen P. Bell

GENES & DEVELOPMENT 21:2897-2907, 2007
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Publication Alert

15-Nov-2007 15:59 | Permalink
The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA

Olga Chilkova, Peter Stenlund, Isabelle Isoz, Carrie M. Stith, Pawel Grabowski, Else-Britt Lundström, Peter M. Burgers and Erik Johansson,

Nucleic Acids Research, 2007, Vol. 35, No. 19 6588-6597
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Publication Alert

06-Nov-2007 18:01 | Permalink
ELYS/MEL-28 Chromatin Association Coordinates Nuclear Pore Complex Assembly and Replication Licensing

Peter J. Gillespie, Guennadi A. Khoudoli, Graeme Stewart, Jason R. Swedlow, and J. Julian Blow

Current Biology, Vol 17, 1657-1662, 09 October 2007
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Publication Alert

06-Nov-2007 18:00 | Permalink
p53-Dependent change in replication timing of the human genome

Yoshihisa Watanabea, Kiyoshi Shibatab, Haruhiko Sugimurac and Masato Maekawaa

Biochemical and Biophysical Research Communications
Volume 364, Issue 2, 14 December 2007, Pages 289-293
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Publication Alert

06-Nov-2007 17:59 | Permalink
Characterization of proliferating cell nuclear antigen (PCNA) isoforms in normal and cancer cells: There is no cancer-associated form of PCNA

Stanislav N. Naryzhny, and Hoyun Leea

Febs leters Volume 581, Issue 25, 16 October 2007, Pages 4917-4920
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Publication Alert

06-Nov-2007 17:57 | Permalink
Drosophila follicle cell amplicons as models for metazoan DNA replication: A cyclinE mutant exhibits increased replication fork elongation

Eugenia A. Park, David M. MacAlpine,, and Terry L. Orr-Weaver

PNAS | October 23, 2007 | vol. 104 | no. 43 | 16739-16746
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Publication Alert

06-Nov-2007 17:55 | Permalink
ATP-dependent Assembly of the Human Origin Recognition Complex

Khalid Siddiqui1 and Bruce Stillman2

J. Biol. Chem., Vol. 282, Issue 44, 32370-32383, November 2, 2007
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Publication Alert

06-Nov-2007 17:53 | Permalink
The Mre11/Rad50/Nbs1 Complex Plays an Important Role in the Prevention of DNA Rereplication in Mammalian Cells

Alan Yueh-Luen Lee, Enbo Liu, and Xiaohua Wu

J. Biol. Chem., Vol. 282, Issue 44, 32243-32255, November 2, 2007
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