Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis

Holger Stephan, Claire Concannon, Elisabeth Kremmer, Michael P. Carty and Heinz-Peter Nasheuer

Nucleic Acids Research, 2009, Vol. 37, No. 18 6028-6041
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Publication Alert

Open chromatin encoded in DNA sequence is the signature of ‘master’ replication origins in human cells

Benjamin Audit, Lamia Zaghloul, Cédric Vaillant, Guillaume Chevereau, Yves d'Aubenton-Carafa, Claude Thermes and Alain Arneodo

Nucleic Acids Research, 2009, Vol. 37, No. 18 6064-6075
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Publication Alert

Aberrant DNA Polymerase α Is Excluded from the Nucleus by Defective Import and Degradation in the Nucleus

Christian S. Eichinger, Takeshi Mizuno, Keiko Mizuno, Yasuyuki Miyake, Ken-ichiro Yanagi, Naoko Imamoto and Fumio Hanaoka

The Journal of Biological Chemistry, 284, 30604-30614.
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Publication Alert

Protein Phosphatase 2A-Dependent Dephosphorylation of Replication Protein A Is Required for the Repair of DNA Breaks Induced by Replication Stress

Junjie Feng, Timothy Wakeman, Sheila Yong, Xiaohua Wu, Sally Kornbluth and Xiao-Fan Wang

Molecular and Cellular Biology, November 2009, p. 5696-5709, Vol. 29, No. 21
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Publication Alert

HOXD13 Binds DNA Replication Origins To Promote Origin Licensing and Is Inhibited by Geminin

Valentina Salsi, Silvia Ferrari, Roberta Ferraresi, Andrea Cossarizza, Alexis Grande, and Vincenzo Zappavigna

Molecular and Cellular Biology, November 2009, p. 5775-5788, Vol. 29, No. 21
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Publication Alert

The annealing helicase HARP protects stalled replication forks

Jingsong Yuan, Gargi Ghosa and Junjie Chen

Genes & Dev. 2009. 23: 2394-2399
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Publication Alert

The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA

Timur Yusufzai, Xiangduo Kong, Kyoko Yokomori and James T. Kadonaga

Genes & Dev. 2009. 23: 2400-2404
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Publication Alert

The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks

Carol E. Bansbach, Rémy Bétous, Courtney A. Lovejoy, Gloria G. Glick and David Cortez

Genes & Dev. 2009. 23: 2405-2414
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Publication Alert

The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart

Alberto Ciccia1, Andrea L. Bredemeyer, Mathew E. Sowa, Marie-Emilie Terret, Prasad V. Jallepalli, J. Wade Harper and Stephen J. Elledge

Genes & Dev. 2009. 23: 2415-2425
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Publication Alert

Transient dsDNA breaks during pre-replication complex assembly

Emmanouil Rampakakis and Maria Zannis-Hadjopoulos

Nucleic Acids Research, 2009, Vol. 37, No. 17 5714-5724
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Publication Alert

Fragile Genomic Sites Are Associated with Origins of Replication

Sara C. Di Rienzi, David Collingwood, M. K. Raghuraman and Bonita J. Brewer

Genome Biology and Evolution (2009) Vol. 2009:350
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Publication Alert

A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase within the eukaryotic replisome

Agnieszka Gambus, Frederick van Deursen, Dimitrios Polychronopoulos, Magdalena Foltman, Richard C Jones, Ricky D Edmondson, Arturo Calzada and Karim Labib

The EMBO Journal (2009) 28, 2992 – 3004
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Publication Alert

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

Xiaohua Xu, Patrick J Rochette, Eminet A Feyissa, Tina V Su and Yilun Liu

The EMBO Journal (2009) 28, 3005 – 3014
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Publication Alert

Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis

Kevin D. Smith, Michael A. Fu, and Eric J. Brown

The Journal of Cell Biology, Vol. 187, No. 1, 15-23
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Publication Alert

Dbf4-Cdc7 Phosphorylation of Mcm2 Is Required for Cell Growth

Irina Bruck and Daniel Kaplan

The Journal of Biological Chemistry, 284, 28823-28831.
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Publication Alert

DNA polymerase ε and δ proofreading suppress discrete mutator and cancer phenotypes in mice

Tina M. Albertson, Masanori Ogawa, James M. Bugni, Laura E. Hays, Yang Chen, Yanping Wang, Piper M. Treuting, John A. Heddle, Robert E. Goldsby and Bradley D. Preston

PNAS October 6, 2009 vol. 106 no. 40 17101-17104
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Publication Alert

C-Terminal Flap Endonuclease (rad27) Mutations: Lethal Interactions With a DNA Ligase I Mutation (cdc9-p) and Suppression by Proliferating Cell Nuclear Antigen (POL30) in Saccharomyces cerevisiae

Kenneth K. Karanja and Dennis M. Livingston

Genetics, Vol. 183, 63-78, September 2009
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