tag:blogger.com,1999:blog-2706107744577821742026-11-06T18:38:01.320+00:00The Blog Site for DNAReplication.netSue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.comBlogger2308125tag:blogger.com,1999:blog-270610774457782174.post-59671553473293213442026-11-06T18:38:01.320+00:002026-11-06T18:38:01.320+00:00<b>Regulation of TIPIN and replication fork dynamics by USP37</b> Benjamin R. Stromberg, Luke Scarberry, Irene S. Cho, and Matthew K. Summers <a href="https://www.molbiolcell.org/doi/10.1091/mbc.E25-08-0391">MBOC Vol. 37, No. 11 November 01, 2026</a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-13196442135814843262026-11-06T18:35:55.767+00:002026-11-06T18:35:55.767+00:00<b>Spontaneous replication fork collapse regulates telomere length homeostasis in wild-type yeast</b> Margherita Paschini, Abigail E. Gillespie, Cynthia M. Reyes, Corinne A. McCoy, Karen A. Lewis, Leslie W. Glustrom, Tatyana O. Sharpee, Deborah S. Wuttke, and Victoria Lundblad <a href="https://doi.org/10.1073/pnas.2536041123">PNAS 123 (44) e2536041123</a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-32134231926934546222026-11-06T18:34:10.555+00:002026-11-06T18:34:10.555+00:00<b>RECQL4 jointly activate the CMG helicase during metazoan DNA replication initiation. </b> Remi Sonneville, Cecile Evrin, Jane Wright, He Huang, Yisui Xia & Karim P M Labib <a href="https://doi.org/10.1038/s44318-026-00915-9">EMBO J 45, 7582–7620 (2026). </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-87327504952334968462026-11-06T18:33:30.460+00:002026-11-06T18:33:30.460+00:00<b>Switch from canonical to recombination-dependent DNA synthesis by M-CDK phosphorylation of DNA Polα </b> Juan de Dios Barba Tena, Riccardo Montecchi, Maxime Lambert, Thomas Defrance, Elisabeth Gueydon, Julie Petit, Marjorie Drac, Noémie Legoff, Michela Galli, Isabelle Goiffon, Thierry Gostan, Khadija El Koulali, Serge Urbach, David Toczyski, Nicolas Talarek & Etienne Schwob <a href="https://link.springer.com/article/10.1038/s44318-026-00919-5?utm_source=springer_etoc&amp;utm_medium=email&amp;utm_campaign=CONR_44318_AWA1_GL_DTEC_054CI_TOC-031126&amp;utm_content=etoc_springer_20261103">Volume 45, pages 7621–7646 (2026) </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-6681491614677773852026-11-06T18:32:25.847+00:002026-11-06T18:32:25.847+00:00<b>MCM10 and RECQL4 have cooperative and redundant roles in activating the CMG helicase during the replication initiation</b> Atabek Bektash, Xiaoxuan Zhu, Yuki Hatoyama, Atsushi Toyoda and Masato T. Kanemak Genes & Dev. 2026. 40: 1825-1836 <a href="https://genesdev.cshlp.org/content/40/21-22/1825.short?rss=1%20"> </a>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-17656022794089459602026-11-06T18:31:38.445+00:002026-11-06T18:31:38.446+00:00<b>ORC1 in health and disease: from DNA replication to cancer</b> <a href="https://doi.org/10.1186/s12967-026-08776-w">J.Translational medicine 2026</a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-70753408531375507282026-11-06T18:30:46.208+00:002026-11-06T18:30:46.208+00:00<b>Molecular Control of Replication Fork Speed: dNTP Availability, Phosphorylation, PARylation, and UFMylation</b> Zheng Li, Akira Shinohara, Yisui Xia, Xingzhi Xu, Shunichi Takeda <a href="https://onlinelibrary.wiley.com/doi/10.1002/bies.70185">Bioessays Volume48, Issue10 October 2026 e70185 </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-30198881955236565092026-11-06T18:29:41.679+00:002026-11-06T18:29:41.679+00:00<b>RNA architecture regulates DNA replication</b> Sabrya Carim <a href="https://www.nature.com/articles/s41556-026-02093-6?utm_source=nature_etoc&amp;utm_medium=email&amp;utm_campaign=CONR_41556_AWA1_GL_DTEC_054CI_TOC-261014&amp;utm_content=20261014">Nature Cell Biology volume 28, page 1979 (2026) </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-29587770322716771602026-11-06T18:28:57.086+00:002026-11-06T18:28:57.086+00:00<b>DNA Polymerase α has Cyclobutane Pyrimidine Dimer Translesion Activity that is Suppressed During Normal Replication</b> Projit Mukherjee , Abheerup Sarker , Grant D. Schauer <a href="https://www.sciencedirect.com/science/article/pii/S002228362600402X">JMB Volume 438, Issue 22 Article: 170029 </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-23597854170633272472026-11-06T18:28:10.636+00:002026-11-06T18:28:10.637+00:00<b>53BP1 condensates regulate DNA replication progression and completion </b> Fangfang Wang, Xinran Geng, Junqiu Zhang, Yen-Jui Su, Franklin Mayca Pozo, Akram Osman, Christophe E. Redon, Anjali Dhall, Michael Leffak, Zihua Gong, Mirit I. Aladjem, Masaru Miyagi, and Youwei Zhang PNAS 123 (41) e2621299123 <a href="https://doi.org/10.1073/pnas.2621299123%20"> </a>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-48642382526513384662026-11-06T18:27:18.523+00:002026-11-06T18:27:18.523+00:00<b>Molecular Control of Replication Fork Speed: dNTP Availability, Phosphorylation, PARylation, and UFMylation</b> Zheng Li, Akira Shinohara, Yisui Xia, Xingzhi Xu, Shunichi Takeda Bioess<a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/bies.70185?campaign=woletoc"></a>ays 10 Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-90044337445036948302026-11-06T18:26:29.182+00:002026-11-06T18:26:29.183+00:00<b>Ubiquitin chain editing promotes p97/VCP-dependent removal of RPA from DNA</b> Matthew Drake ∙ Xianzhen Zhou ∙ Alexandra McStea ∙ Benjamin Foster∙ Kay Yi Chong ∙ Martin Attwood ∙ Leslye Roca Burgos ∙ Laura Bennett ∙ Sneha Anand∙ Merve Kaplan∙ Jessica J. Lu∙ Vaishnavi Ravikumar ∙ Marjorie Fournier ∙ Elena Navarro-Guerrero ∙ Michael Ranes ∙ Weston B. Struwe ∙ Christopher Staples ∙ Daniel Ebner ∙ Ian Gibbs-Seymour <a href="https://www.cell.com/molecular-cell/fulltext/S1097-2765%2826%2900621-0?dgcid=raven_jbs_etoc_email%20">Molecular Cell, 86, 3897-3914.e18 </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-47711121449981114452026-11-06T18:25:41.269+00:002026-11-06T18:25:41.270+00:00<b>Human PIF1 clears secondary DNA structures by coupled DNA unwinding and rewinding activities </b> Akshay Jayachandran, Martin Mütze, Kostiantyn Romaniuk, Jessica J.R. Hudson, Maria Rosaria Dello Stritto, Raphaël Guérois, Ananya Acharya, Stefan Braunshier, Giordano Reginato, Issam Senoussi, Ulrich Rass3 Ralf Seidel and Petr Cejka. <a href="https://genesdev.cshlp.org/content/40/19-20/1747.abstract?etoc%20">Genes & Dev. 2026. 40: 1747-1764 </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-64421320910167960812026-11-06T18:24:41.081+00:002026-11-06T18:24:41.081+00:00<b>Molecular basis of DNA polymerase ζ’s reverse transcriptase activity</b> Radhika Malik, Robert E. Johnson, Louise Prakash, Satya Prakash & Aneel K. Aggarwal <a href="https://www.nature.com/articles/s41467-026-78032-8">Nature Communications (2026) </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-78358733663101162502026-11-06T18:23:45.558+00:002026-11-06T18:23:45.558+00:00<b>Dysregulation of DNA replication licensing factors in cancer </b> Spyridon Champeris Tsaniras & George Delinasios <a href="https://link.springer.com/article/10.1186/s10020-026-01646-7?utm_source=bmc_etoc&amp;utm_medium=email&amp;utm_campaign=CONR_10020_AWA1_GL_DTEC_054CI_TOC-261001">BMC molecular medicine </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-18016094779075333732026-11-06T18:22:40.802+00:002026-11-06T18:22:40.803+00:00<b>DNA binding contributes to dominant-negative effects of a catalytically inactive RecQ4-family helicase </b> Robert H Simmons, III, Faith E McDevitt, Alexandra Hurlock, Michael E Kumcu, Matthew L Bochman <a href="https://doi.org/10.1093/nar/gkag903%20">Nucleic Acids Research, Volume 54, Issue 17, 23 September 2026, gkag903, </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-618301708966550142026-11-06T18:21:39.570+00:002026-11-06T18:21:39.570+00:00<b>Three-dimensional chromatin architecture is rapidly restored after DNA replication</b> Tyler K. Fenstermaker, Svetlana Petruk & Alexander Mazo  <a href="https://www.nature.com/articles/s41467-026-77901-6">Nature Communications (2026) </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-1145463465486180402026-11-06T18:20:48.192+00:002026-11-06T18:20:48.192+00:00<b>Cohesin reshapes replication fork contacts to aid fork slowing and reversal</b> Daniel González-Acosta, Daniel Giménez-Llorente, Melani Rodrigues, Moses Aouami, Orhi Barroso-Gomila, Javier Muñoz, Ana Cuadrado, Ana Losada & Massimo Lopes Nature (2026). <a href="https://doi.org/10.1038/s41586-026-11034-0%20"></a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-10769912546758107292026-09-04T17:38:38.258+01:002026-09-04T17:38:38.259+01:00<b>Recent advances on mammalian DNA replication initiation and timing: From chromatin features to nuclear organization</b> Rocío Nunez-Vazquez, Geneviève Almouzni Current Opinion in Structural Biology Volume 98, June 2026, 103274 <a href="https://www.sciencedirect.com/science/article/pii/S0959440X26000564"></a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-86396221759736944542026-09-04T17:37:51.432+01:002026-09-04T17:37:51.432+01:00<b>Partitioning of parental histones between leading and lagging strands is modulated by DNA polymerase dosage </b> Quinn Dickinson , Srinivasu Karri , Odile Djom Kenmogne , Shuang Zhu , Juan Carlos Rivera-Mulia , Zhenqing Ye , Zhiquan Wang , Haiyun Gan , Chuanhe Yu <a href="about:invalid#zSoyz">Nucleic Acids Research, Volume 54, Issue 15, 27 August 2026, gkag787</a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-6214311125285710652026-09-04T17:36:57.974+01:002026-09-04T17:36:57.974+01:00<b>FANCJ and RTEL1 facilitate pre-replication complex disassembly following replisome collision</b> George Cameron ∙ Simran Negi ∙ Koichi Sato ∙ Sevim Yardimci ∙ Çağla Kaya ∙ Cameron McClymont ∙ Anoop Kumar Yadav ∙ Jana Krejci ∙ Puck Knipscheer ∙ Hana Polasek-Sedlackova∙ Hasan Yardimci <a href="https://www.cell.com/cell-reports/fulltext/S2211-1247%2826%2900938-1%20">Cell Reports, 2026; 45 </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-57285362330559359972026-09-04T17:36:04.298+01:002026-09-04T17:36:04.299+01:00<b>Structural insights into Sld3-Sld7-dependent Cdc45 loading during replication initiation</b> Yasunori Noguchi, Almutasem Saleh, Sarah Schneider, Marina E. Ivanova, Zhuo Angel Chen, Lepakshi Ranjha, Ricardo Aramayo, Silvia Tognetti, Sarah V. Faull, Juri Rappsilber & Christian Speck <a href="https://doi.org/10.1038/s41467-026-76309-6%20">Nat Commun (2026). </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-81877868017741191612026-09-04T17:35:10.262+01:002026-09-04T17:35:10.262+01:00<b>Mechanistic diversity of clamp loading at small DNA gaps </b> Fengwei Zheng ∙ Michael E. O’Donnell ∙ Huilin Li <a href="https://www.jbc.org/article/S0021-9258%2826%2902269-6/fulltext">JBC REVIEWSArticles in Press113397August 2026 </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-67928926524589620482026-09-04T17:34:20.899+01:002026-09-04T17:34:20.899+01:00<b>Pol γ possesses separate metal binding sites for polymerase and strand displacement functions </b> Noe Baruch-Torres , Joon Park , Josue Mora-Garduño , Arkanil Roy , Anupam Singh , G Andrés Cisneros , Luis G Brieba , Smita S Patel , Y Whitney Yin <a href="https://doi.org/10.1093/nar/gkag720%20%20">Nucleic Acids Research, Volume 54, Issue 14, 12 August 2026, gkag720, </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-24574456331736774862026-09-04T17:33:23.441+01:002026-09-04T17:33:23.442+01:00<b>TTF2 processes sites of incomplete DNA replication during mitosis via sister-chromatid exchanges</b> RYO FUJISAWA AND KARIM P. M. LABIB <a href="https://www.science.org/doi/10.1126/science.aeh2300%20">SCIENCE 2 Jul 2026Vol 393, Issue 6812 </a> Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0