tag:blogger.com,1999:blog-2706107744577821742010-09-06T15:01:23.275+01:00The Blog Site for DNAReplication.netSue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.comBlogger573125tag:blogger.com,1999:blog-270610774457782174.post-7135252144230089552010-09-06T15:00:00.002+01:002010-09-06T15:01:23.284+01:00<span style="font-weight:bold;">Specific replication origins promote DNA amplification in fission yeast</span><br /><br />Lee Kiang, Christian Heichinger, Stephen Watt, Jürg Bähler and Paul Nurse<br /><br /><a href="http://jcs.biologists.org/cgi/content/abstract/123/18/3047">Journal of Cell Science 123, 3047-3051 (2010)</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-713525214423008955?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-84598852929366405522010-09-06T15:00:00.001+01:002010-09-06T15:00:36.969+01:00<span style="font-weight:bold;">IKK and NF-κB-mediated regulation of Claspin impacts on ATR checkpoint function</span><br /><br />Niall Steven Kenneth, Sharon Mudie and Sonia Rocha<br /><br /><a href="http://www.nature.com/emboj/journal/v29/n17/abs/emboj2010171a.html">The EMBO Journal (2010) 29, 2966 – 2978</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-8459885292936640552?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-47848061773332957142010-09-06T14:59:00.000+01:002010-09-06T15:00:04.906+01:00<span style="font-weight:bold;">Components of the Secondary Pathway Stimulate the Primary Pathway of Eukaryotic Okazaki Fragment Processing</span><br /><br />Ryan A. Henry, Lata Balakrishnan, Stefanie Tan Ying-Lin, Judith L. Campbell and Robert A. Bambara<br /><br /><a href="http://www.jbc.org/content/285/37/28496.abstract?etoc">Journal of Biological Chemistry, 285, 28496-28505.</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-4784806177333295714?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-85930555377616375082010-09-06T14:58:00.000+01:002010-09-06T14:59:26.475+01:00<span style="font-weight:bold;">Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions</span><br /><br />Sophie Gay, Anne-Marie Lachages, Gael A Millot, Sylvain Courbet, Anne Letessier, Michelle Debatisse & Olivier Brison<br /><br /><a href="http://www.nature.com/embor/journal/v11/n9/abs/embor2010112.html">EMBO reports (2010) 11, 698 – 704</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-8593055537761637508?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-44691592070509027872010-09-06T14:57:00.002+01:002010-09-06T14:58:34.048+01:00<span style="font-weight:bold;">Multiple Functions for Drosophila Mcm10 Suggested Through Analysis of Two Mcm10 Mutant Alleles</span><br /><br />Jennifer Apger, Michael Reubens, Laura Henderson, Catherine A. Gouge, Nina Ilic, Helen H. Zhou and Tim W. Christensen<br /><br /><a href="http://www.genetics.org/cgi/content/abstract/185/4/1151">Genetics, Vol. 185, 1151-1165, August 2010</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-4469159207050902787?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-63162719662391493422010-09-06T14:57:00.001+01:002010-09-06T14:57:53.628+01:00Control of DNA replication: A new facet of Hox proteins?<br /><br />Benoit Miotto and Yacine Graba<br /><br /><a href="http://onlinelibrary.wiley.com/doi/10.1002/bies.201000048/abstract">BioEssays Volume 32, Issue 9, pages 800–807, September 2010</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-6316271966239149342?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-72103041358855944702010-08-30T14:43:00.000+01:002010-08-30T14:44:06.092+01:00<span style="font-weight:bold;">Pre-Steady State Kinetic Studies of the Fidelity of Nucleotide Incorporation by Yeast DNA Polymerase δ</span><br /> <br />Lynne M. Dieckman, Robert E. Johnson, Satya Prakash and M. Todd Washington<br /><a href="http://pubs.acs.org/doi/abs/10.1021/bi100556m"></a><br />Biochemistry, 2010, 49 (34), pp 7344–7350<div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-7210304135885594470?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-18277645573751565752010-08-30T14:42:00.000+01:002010-08-30T14:43:18.466+01:00<span style="font-weight:bold;">Methylated DNA Causes a Physical Block to Replication Forks Independently of Damage Signalling, O6-Methylguanine or DNA Single-Strand Breaks and Results in DNA Damage</span><br /><br />Petra Groth, Simon Ausländer, Muntasir Mamun Majumder, Niklas Schultz, Fredrik Johansson, Eva Petermann and Thomas Helleday<br /><br /><a href="http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WK7-50JHC3T-1&_user=10&_coverDate=09%2F10%2F2010&_rdoc=9&_fmt=high&_orig=browse&_origin=browse&_zone=rslt_list_item&_srch=doc-info(%23toc%236899%232010%23995979998%232305758%23FLA%23display%23Volume)&_cdi=6899&_sort=d&_docanchor=&_ct=24&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=ea6aecc1ae64fd0d2227cb3d9b3807f0&searchtype=a">Journal of Molecular Biology Volume 402, Issue 1, 10 September 2010, Pages 70-82</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-1827764557375156575?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-43119911025225966402010-08-30T14:41:00.002+01:002010-08-30T14:42:27.420+01:00<span style="font-weight:bold;">Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization</span><br /><br />Supriya G. Prasantha, Zhen Shen, Kannanganattu V. Prasanth, and Bruce Stillman<br /><br /><a href="http://www.pnas.org/content/107/34/15093.abstract">PNAS August 24, 2010 vol. 107 no. 34 15093-15098</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-4311991102522596640?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-72476872974301946562010-08-30T14:41:00.001+01:002010-08-30T14:41:40.762+01:00<span style="font-weight:bold;">A chromatin-bound kinase, ERK8, protects genomic integrity by inhibiting HDM2-mediated degradation of the DNA clamp PCNA</span><br /><br />Angela L. Groehler and Deborah A. Lannigan<br /><br /><a href="http://jcb.rupress.org/content/190/4/575.abstract">JCB vol. 190 no. 4 575-586</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-7247687297430194656?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-17657530576675692182010-08-30T14:39:00.000+01:002010-08-30T14:41:04.443+01:00<span style="font-weight:bold;">Replication Termination at Eukaryotic Chromosomes Is Mediated by Top2 and Occurs at Genomic Loci Containing Pausing Elements</span><br /><br />Daniele Fachinetti,Rodrigo Bermejo,Andrea Cocito,Simone Minardi,Yuki Katou,Yutaka Kanoh,Katsuhiko Shirahige,Anna Azvolinsky,Virginia A. Zakian, Marco Foiani<br /><br /><a href="http://www.cell.com/molecular-cell/abstract/S1097-2765(10)00571-X">Molecular Cell, Volume 39, Issue 4, 595-605, 27 August 2010</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-1765753057667569218?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-87613463353644992122010-08-21T06:49:00.001+01:002010-08-21T06:49:35.398+01:00<span style="font-weight:bold;">Loss of DNA Replication Control Is a Potent Inducer of Gene Amplification</span><br /><br />Brian M. Green, Kenneth J. Finn, and Joachim J. Li<br /><br /><a href="http://www.sciencemag.org/cgi/content/abstract/329/5994/943">Science 20 August 2010: 943-946.</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-8761346335364499212?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-996380934194303722010-08-21T06:48:00.001+01:002010-08-21T06:48:57.721+01:00<span style="font-weight:bold;">Regulation of heterochromatic DNA replication by histone H3 lysine 27 methyltransferases</span><br /><br />Yannick Jacob, Hume Stroud, Chantal LeBlanc, Suhua Feng, Luting Zhuo, Elena Caro, Christiane Hassel, Crisanto Gutierrez, Scott D. Michaels & Steven E. Jacobsen<br /><br /><a href="http://www.nature.com/nature/journal/v466/n7309/abs/nature09290.html">Nature 466, 987–991 (19 August 2010)</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-99638093419430372?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-89809957781760401882010-08-21T06:47:00.000+01:002010-08-21T06:48:07.891+01:00<span style="font-weight:bold;">FEN1 Ensures Telomere Stability by Facilitating Replication Fork Re-initiation</span><br /> <br />Abhishek Saharia, Daniel C. Teasley, Julien P. Duxin, Benjamin Dao, Katherine B. Chiappinelli, and Sheila A. Stewart<br /> <br /><a href=" http://www.jbc.org/cgi/content/abstract/285/35/27057?etoc">J. Biol. Chem. 2010 285: 27057-27066. </a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-8980995778176040188?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-78221589363563255832010-08-16T16:35:00.000+01:002010-08-16T16:37:01.970+01:00<span style="font-weight:bold;">Homologous Recombination Restarts Blocked Replication Forks at the Expense of Genome Rearrangements by Template Exchange</span><br /><br />Sarah Lambert,Ken'ichi Mizuno,Joël Blaisonneau,Sylvain Martineau,Roland Chanet,Karine Fréon,Johanne M. Murray,Antony M. Carr,Giuseppe Baldacci<br /><br /><a href="http://www.cell.com/molecular-cell/abstract/S1097-2765(10)00537-X">Molecular Cell, Volume 39, Issue 3, 346-359, 13 August 2010</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-7822158936356325583?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-38520288623682261432010-08-16T16:34:00.000+01:002010-08-16T16:35:43.390+01:00<span style="font-weight:bold;">Regulation of DNA Repair through DeSUMOylation and SUMOylation of Replication Protein A Complex</span><br /><br />Hong Dou,Chao Huang,Melissa Singh,Phillip B. Carpenter,Edward T.H. Yeh<br /><br /><a href="http://www.cell.com/molecular-cell/abstract/S1097-2765(10)00567-8">Molecular Cell, Volume 39, Issue 3, 333-345, 13 August 2010</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-3852028862368226143?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-37039586774912335332010-08-09T10:23:00.002+01:002010-08-09T10:24:40.606+01:00<span style="font-weight:bold;">Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase ϵ in the presence of replication protein A and proliferating-cell nuclear antigen</span><br /><br />Giada A. Locatelli, Helmut Pospiech, Nicolas Tanguy Le Gac, Barbara van Loon, Ulrich Hubscher, Sinikka Parkkinen, Juhani E. Syväoja and Giuseppe Villani<br /><br /><a href="http://www.biochemj.org/bj/429/bj4290573.htm">Biochem. J. (2010) 429 (573–582)</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-3703958677491233533?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-10523914430534406022010-08-09T10:23:00.001+01:002010-08-09T10:23:50.411+01:00<span style="font-weight:bold;">Accessibility of the Drosophila genome discriminates PcG repression, H4K16 acetylation and replication timing</span><br /><br />Oliver Bell, Michaela Schwaiger, Edward J Oakeley, Florian Lienert, Christian Beisel, Michael B Stadler & Dirk Schübeler<br /><br /><a href="http://www.nature.com/nsmb/journal/v17/n7/abs/nsmb.1825.html">Nature Structural & Molecular Biology 17, 894–900 (2010)</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-1052391443053440602?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-71186888929893115312010-08-09T10:22:00.000+01:002010-08-09T10:23:21.174+01:00<span style="font-weight:bold;">Geminin and Brahma act antagonistically to regulate EGFR–Ras–MAPK signaling in Drosophila</span><br /><br />Anabel Herr, Lisa Mckenzie, Randy Suryadinata, Martin Sadowski, Linda M. Parsons, Boris Sarcevic and Helena E. Richardson<br /><br /><a href="http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WDG-4YWYYYX-1&_user=10&_coverDate=08%2F01%2F2010&_rdoc=7&_fmt=high&_orig=browse&_srch=doc-info(%23toc%236766%232010%23996559998%232226755%23FLA%23display%23Volume)&_cdi=6766&_sort=d&_docanchor=&_ct=465&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=177708def16ff6fb2e39c69a04b645c2">Developmental Biology Volume 344, Issue 1, 1 August 2010, Pages 36-51</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-7118688892989311531?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-5450407981287592922010-08-09T10:21:00.002+01:002010-08-09T10:22:16.033+01:00<span style="font-weight:bold;">Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase</span><br /><br />Sivaraja Vaithiyalingam, Eric M. Warren, Brandt F. Eichman, and Walter J. Chazin<br /><br /><a href="http://www.pnas.org/content/107/31/13684.abstract">PNAS August 3, 2010 vol. 107 no. 31 13684-13689</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-545040798128759292?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-50130761183832652182010-08-09T10:21:00.001+01:002010-08-09T10:21:25.651+01:00<span style="font-weight:bold;">Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling</span><br /><br />Jun-Hyuk Choia, Laura A. Lindsey-Boltza, Michael Kempa, Aaron C. Masonb, Marc S. Woldb, and Aziz Sancara<br /><br /><a href="http://www.pnas.org/content/107/31/13660.abstract">PNAS August 3, 2010 vol. 107 no. 31 13660-13665</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-5013076118383265218?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-3967447416650409972010-08-09T10:20:00.001+01:002010-08-09T10:20:59.596+01:00<span style="font-weight:bold;">Identification of a Coiled Coil in Werner Syndrome Protein That Facilitates Multimerization and Promotes Exonuclease Processivity</span><br /> <br />J. Jefferson P. Perry, Aroumougame Asaithamby, Adam Barnebey, Foad Kiamanesch, David J. Chen, Seungil Han, John A. Tainer, and Steven M. Yannone<br /> <br /><a href=" http://www.jbc.org/cgi/content/abstract/285/33/25699?etoc">J. Biol. Chem. 2010 285: 25699-25707. </a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-396744741665040997?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-92048510949630553822010-08-09T10:19:00.000+01:002010-08-09T10:20:12.072+01:00<span style="font-weight:bold;">The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication</span><br /><br />Rebecca L. Ferguson, Gaetan Pascreau and James L. Maller<br /><br /><a href="http://jcs.biologists.org/cgi/content/abstract/123/16/2743">Journal of Cell Science 123, 2743-2749 (2010)</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-9204851094963055382?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-68620369372139035902010-08-09T10:18:00.000+01:002010-08-09T10:19:18.517+01:00<span style="font-weight:bold;">Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA</span><br /><br />Oren Parnas, Adi Zipin-Roitman, Boris Pfander, Batia Liefshitz, Yuval Mazor, Shay Ben-Aroya, Stefan Jentsch and Martin Kupiec<br /><br /><a href="http://www.nature.com/emboj/journal/v29/n15/abs/emboj2010128a.html">The EMBO Journal (2010), 29, 2611 - 2622; </a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-6862036937213903590?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0tag:blogger.com,1999:blog-270610774457782174.post-84269750929927566062010-08-02T13:31:00.000+01:002010-08-02T13:32:01.925+01:00<span style="font-weight:bold;">Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA</span><br /><br />Máté Gyimesi1, Kata Sarlós1 and Mihály Kovács<br /><br /><a href="http://nar.oxfordjournals.org/cgi/content/abstract/38/13/4404">Nucleic Acids Research, 2010, Vol. 38, No. 13 4404-4414
</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/270610774457782174-8426975092992756606?l=dnarepnet.blogspot.com' alt='' /></div>Sue Cotterillhttp://www.blogger.com/profile/02135935985771594471noreply@blogger.com0