Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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23-Feb-2015 09:27 | Permalink
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17-Feb-2015 08:29 | Permalink
Structural insight into how the human helicase subunit MCM2 may act as a histone chaperone together with ASF1 at the replication fork Nicolas Richet, Danni Liu, Pierre Legrand, Christophe Velours, Armelle Corpet, Albane Gaubert, May Bakail, Gwenaelle Moal-Raisin, Raphael Guerois, Christel Compper, Arthur Besle, Berengère Guichard, Genevieve Almouzni, and Françoise Ochsenbein Nucl. Acids Res. 2015 43: 1905-1917
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17-Feb-2015 08:28 | Permalink
Dynamic loading and redistribution of the Mcm2‐7 helicase complex through the cell cycle Sara K Powell, Heather K MacAlpine, Joseph A Prinz, Yulong Li, Jason A Belsky, David M MacAlpine Embo j Volume 34, Issue 4 12 February 2015 | pp 425 – 577
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09-Feb-2015 09:46 | Permalink
Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication Emma L Hesketh, John RP Knight, Rosemary HC Wilson, James PJ Chong & Dawn Coverley Cell Cycle Volume 14, Issue 3, 2015
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09-Feb-2015 09:46 | Permalink
Opening the gate to DNA replication Alberto Rieraa & Christian Speck Cell cycle 14 6-8
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09-Feb-2015 09:45 | Permalink
DNA-protein interaction dynamics at the Lamin B2 replication origin Luca Puzzi, Laura Marchetti, Fiorenzo A Peverali, Giuseppe Biamonti & Mauro Giacca
 Cell cycle 14 pages 64-73
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09-Feb-2015 09:44 | Permalink
Yeast DNA Polymerase ϵ Catalytic Core and Holoenzyme Have Comparable Catalytic Rates Rais A. Ganai, Pia Osterman, and Erik Johansson J. Biol. Chem. 2015; 290:3825-3835
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09-Feb-2015 09:44 | Permalink
Interaction of Chk1 with Treslin Negatively Regulates the Initiation of Chromosomal DNA Replication Cai Guo, Akiko Kumagai, Katharina Schlacher, Anna Shevchenko, Andrej Shevchenko, William G. Dunphy Mol cell Volume 57, Issue 3, p492–505, 5 February 2015
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02-Feb-2015 09:55 | Permalink
Genome-wide chromatin footprinting reveals changes in replication origin architecture induced by pre-RC assembly Jason A. Belsky, Heather K. MacAlpine, Yoav Lubelsky, Alexander J. Hartemink and David M. MacAlpine Genes & Dev. 2015. 29: 212-224
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02-Feb-2015 09:53 | Permalink
Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement Tatjana Petojevic, James J. Pesavento, Alessandro Costa, Jingdan Liang, Zhijun Wang, James M. Berger, and Michael R. Botchan PNAS 2015 112 (3) E249-E258;
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02-Feb-2015 09:50 | Permalink
Switching between polymerase and exonuclease sites in DNA polymerase ε Rais A. Ganai, Göran O. Bylund, and Erik Johansson Nucl. Acids Res. 2015 43: 932-942
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02-Feb-2015 09:49 | Permalink
Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins Thomas A. Guilliam, Stanislaw K. Jozwiakowski, Aaron Ehlinger, Ryan P. Barnes, Sean G. Rudd, Laura J. Bailey, J. Mark Skehel, Kristin A. Eckert,Walter J. Chazin, and Aidan J. Doherty Nucl. Acids Res. 2015 43: 1056-1068
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02-Feb-2015 09:49 | Permalink
The Dbf4-Cdc7 Kinase Promotes Mcm2-7 Ring Opening to Allow for Single-stranded DNA Extrusion and Helicase Assembly Irina Bruck and Daniel L. Kaplan1 The Journal of Biological Chemistry, 290, 1210-1221.
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02-Feb-2015 09:48 | Permalink
Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function Jingchuan Sun,Alejandra Fernandez-Cid, Alberto Riera, Silvia Tognetti, Zuanning Yuan, Bruce Stillman, Christian Speck and Huilin Li1, Genes & Dev. 2014. 28: 2291-2303
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