Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

Publication Alert

30-Nov-2009 10:44 | Permalink
PCNA Is Required for Initiation of Recombination-Associated DNA Synthesis by DNA Polymerase δ

Xuan Li1, Carrie M. Stith, Peter M. Burgers and Wolf-Dietrich Heyer

Molecular Cell, Volume 36, Issue 4, 704-713, 25 November 2009
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Publication Alert

30-Nov-2009 10:44 | Permalink
Csm3, Tof1, and Mrc1 Form a Heterotrimeric Mediator Complex That Associates with DNA Replication Forks

Masashige Bando, Yuki Katou, Makiko Komata, Hirokazu Tanaka, Takehiko Itoh, Takashi Sutani and Katsuhiko Shirahige

The Journal of Biological Chemistry, 284, 34355-34365.
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Publication Alert

30-Nov-2009 10:41 | Permalink
Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

V. De Marco, P. J. Gillespie, A. Li, N. Karantzelis, E. Christodoulou, R. Klompmaker, S. van Gerwen, A. Fish, M. V. Petoukhov, M. S. Iliou, Z. Lygerou, R. H. Medema, J. J. Blow, D. I. Svergun, S. Taraviras and A. Perrakis

PNAS November 24, 2009 vol. 106 no. 47 19807-19812
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Publication Alert

30-Nov-2009 10:41 | Permalink
The Mechanistic Architecture of Thermostable Pyrococcus furiosus Family B DNA Polymerase Motif A and Its Interaction with the dNTP Substrate

Edward M. Kennedy, Christopher Hergott, Stephen Dewhurst and Baek Kim


Biochemistry, 2009, 48 (47), pp 11161–11168
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Publication Alert

23-Nov-2009 10:47 | Permalink
Reconstitution of Human Claspin-mediated Phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) Checkpoint Kinase

Laura A. Lindsey-Boltz, Özdemirhan Serçin, Jun-Hyuk Choi and Aziz Sancar

The Journal of Biological Chemistry, 284, 33107-33114.
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Publication Alert

23-Nov-2009 10:47 | Permalink
Herpes Simplex Virus-1 DNA Primase: A Remarkably Inaccurate yet Selective Polymerase

Milan Urban, Nicolas Joubert, Michal Hocek, Richard E. Alexander and Robert D. Kuchta

Biochemistry, 2009, 48 (46), pp 10866–10881
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Publication Alert

16-Nov-2009 09:42 | Permalink
Putting Two Heads Together to Unwind DNA

Thomas J. Takara, 2 and Stephen P. Bell

Cell, Volume 139, Issue 4, 652-654, 13 November 2009
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Publication Alert

16-Nov-2009 09:41 | Permalink
Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing

Dirk Remus, Fabienne Beuron, Gökhan Tolun, Jack D. Griffith, Edward P. Morris and John F.X. Diffley,

Cell, Volume 139, Issue 4, 719-730, 05 November 2009
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Publication Alert

16-Nov-2009 09:41 | Permalink
Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress

Vitaly M. Vassin, Rachel William Anantha, Elena Sokolova, Shlomo Kanner and James A. Borowiec

Journal of Cell Science 122, 4070-4080
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Publication Alert

16-Nov-2009 09:40 | Permalink
Structural Insights into Yeast DNA Polymerase δ by Small Angle X-ray Scattering

Rinku Jain, Michal Hamme, Robert E. Johnson, Louise Prakash, Satya Prakash and Aneel K. Aggarwal

Journal of Molecular Biology Volume 394, Issue 3, 4 December 2009, Pages 377-382
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Publication Alert

16-Nov-2009 09:39 | Permalink
Cohesin acetylation speeds the replication fork

Marie-Emilie Terret, Rebecca Sherwood, Sadia Rahman, Jun Qin2 & Prasad V. Jallepalli

Nature 462, 231-234 (12 November 2009)
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Publication Alert

09-Nov-2009 18:57 | Permalink
Translesion Synthesis of Abasic Sites by Yeast DNA Polymerase ϵ

Nasim Sabouri1 and Erik Johansson

The Journal of Biological Chemistry, 284, 31555-31563.
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Publication Alert

09-Nov-2009 18:56 | Permalink
Binding to PCNA in Euryarchaeal DNA Replication Requires Two PIP Motifs for DNA Polymerase D and One PIP Motif for DNA Polymerase B

Benoît Castrec, Christophe Rouillon, Ghislaine Henneke, Didier Flament, Joël Querellou, and Jean-Paul Raffin

Journal of Molecular Biology Volume 394, Issue 2, 27 November 2009, Pages 209-218
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Publication Alert

02-Nov-2009 09:45 | Permalink
Human Pif1 helicase unwinds synthetic DNA structures resembling stalled DNA replication forks

Tresa George, Qin Wen, Richard Griffiths, Anil Ganesh, Mark Meuth and Cyril M. Sanders

Nucleic Acids Research, 2009, Vol. 37, No. 19 6491-6502
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Publication Alert

02-Nov-2009 09:45 | Permalink
Drosophila RecQ4 Has a 3′-5′ DNA Helicase Activity That Is Essential for Viability*

Christopher Capp, Jianhong Wu and Tao-shih Hsieh

The Journal of Biological Chemistry, 284, 30845-30852.
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Publication Alert

02-Nov-2009 09:43 | Permalink
Herpes Simplex Virus-1 Helicase−Primase: Roles of Each Subunit in DNA Binding and Phosphodiester Bond Formation

Nisha A. Cavanaugh, Kathryn A. Ramirez-Aguilar, Milan Urban and Robert D. Kuchta

Biochemistry, 2009, 48 (43), pp 10199–10207
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Publication Alert

02-Nov-2009 09:41 | Permalink
Global Conformational Dynamics of a Y-Family DNA Polymerase during Catalysis

Cuiling Xu1, Brian A. Maxwell2, Jessica A. Brown1,3, Likui Zhang1, Zucai Suo

PLoS Biol 7(10): e1000225
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Publication Alert

02-Nov-2009 09:40 | Permalink
A Reduction in Ribonucleotide Reductase Activity Slows Down the Chromosome Replication Fork but Does Not Change Its Localization

Ingvild Odsbu, Morigen, Kirsten Skarstad

PLoS ONE 4(10): e7617
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