Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

publication alert

17-Dec-2018 11:24 | Permalink
Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks Romain Drissi, Anaïs Chauvin, Alyson McKenna, Dominique Lévesque, Simon Blais-Brochu, Dominique Jean & François-Michel Boisvert Cell Cycle, 17:23, 2593-2609
Comments

publication alert

17-Dec-2018 11:05 | Permalink
A structural view of the initiators for chromosome replication Kin Fan On, Matt Jaremko, Bruce Stillman, Leemor Joshua-Tor Current Opinion in Structural Biology Volume 53, December 2018, Pages 131-139
Comments

publication alert

17-Dec-2018 11:04 | Permalink
Eukaryotic DNA polymerases Rinku Jain, Aneel Aggarwal, Olga Rechkoblit Current Opinion in Structural Biology Volume 53, December 2018, Pages 77-87
Comments

publication alert

17-Dec-2018 10:51 | Permalink
CDK phosphorylation regulates Mcm3 degradation in budding yeast KaoriYamamoto, NishihoMakino, MasayoshiNagai, HiroyukiAraki, TakashiUshimaru Biochemical and Biophysical Research Communications Volume 506, Issue 3, 30 November 2018, Pages 680-684 https://www.sciencedirect.com/science/article/pii/S0006291X18323283
Comments

publication alert

17-Dec-2018 09:49 | Permalink
Pif1 is essential for efficient replisome progression through lagging strand G-quadruplex DNA secondary structures Danielle Dahan Ioannis Tsirkas Daniel Dovrat Melanie A Sparks Saurabh P Singh Roberto Galletto Amir Aharoni Nucleic Acids Research, Volume 46, Issue 22, 14 December 2018, Pages 11847–11857,
Comments

publication alert

10-Dec-2018 09:27 | Permalink
Conformational Flexibility of Ubiquitin-Modified and SUMO-Modified PCNA Shown by Full-Ensemble Hybrid Methods Kyle T.Powers Emily D.Lavering M. ToddWashington Journal of Molecular Biology Volume 430, Issue 24, 7 December 2018, Pages 5294-5303
Comments

publication alert

10-Dec-2018 09:24 | Permalink
Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome OPEN Panchali Goswami, Ferdos Abid Ali, Max E. Douglas, Julia Locke, Andrew Purkiss, Agnieszka Janska, Patrik Eickhoff, Anne Early, Andrea Nans, Alan M. C. Cheung, John F. X. Diffley & Alessandro Costa 29 November 2018 | doi: 10.1038/s41467-018-07417-1
Comments

publication alert

10-Dec-2018 09:23 | Permalink
Proliferating cell nuclear antigen interacts with the CRL4 ubiquitin ligase subunit CDT2 in DNA synthesis–induced degradation of CDT1 Feng Leng, Lovely Saxena, Nam Hoang, Chunxiao Zhang, Logan Lee, Wenjing Li, Xiaoshan Gong, Fei Lu, Hong Sun and Hui Zhang J. Biol. Chem. 2018; 293:18879-18889
Comments

publication alert

10-Dec-2018 09:23 | Permalink
Regulation of the Minichromosome Maintenance Protein 3 (MCM3) Chromatin Binding by the Prolyl Isomerase Pin1 Michael Schumann, Miroslav Malešević, Erik Hinze, Sebastian Mathea, ... Cordelia Schiene-Fischer J Mol Biol Volume 430, Issue 24, 7 December 2018, Pages 5169-5181
Comments

publication alert

10-Dec-2018 09:02 | Permalink
Cdt1 variants reveal unanticipated aspects of interactions with cyclin/CDK and MCM important for normal genome replication Pedro N. Pozo, Jacob P. Matson, Yasemin Cole, Katarzyna M. Kedziora, Gavin D. Grant, Brenda Temple, and Jeanette Gowen Cook Molecular Biology of the Cell 29 Pages:2989–3002
Comments