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07-Dec-2021 12:03
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Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites
Shyam Twayana, Albino Bacolla, Angelica Barreto-Galvez, Ruth B. De-Paula, William C. Drosopoulos, Settapong T. Kosiyatrakul, Eric E. Bouhassira, John A. Tainer, Advaitha Madireddy, and Carl L. Schildkraut
PNAS November 30, 2021 118 (48) e2106477118;
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07-Dec-2021 12:01
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The genetic architecture of DNA replication timing in human pluripotent stem cells
Qiliang Ding, Matthew M. Edwards, Ning Wang, Xiang Zhu, Alexa N. Bracci, Michelle L. Hulke, Ya Hu, Yao Tong, Joyce Hsiao, Christine J. Charvet, Sulagna Ghosh, Robert E. Handsaker, Kevin Eggan, Florian T. Merkle, Jeannine Gerhardt, Dieter Egli, Andrew G. Clark & Amnon Koren
Nature Communications volume 12, Article number: 6746 (2021)
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07-Dec-2021 11:59
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Molecular Mechanisms of the RECQ4 Pathogenic Mutations
Xiaohua Xu, Chou-Wei Chang, Min Li, Chao Liu and Yilun Liu
Front. Mol. Biosci., 18 November 2021
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07-Dec-2021 11:57
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Replication timing analysis in polyploid cells reveals Rif1 uses multiple mechanisms to promote underreplication in Drosophila
Souradip Das, Madison Caballero, Tatyana Kolesnikova, Igor Zhimulev, Amnon Koren, Jared Nordman
Genetics, Volume 219, Issue 3, November 2021, iyab147,
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07-Dec-2021 11:55
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Error-prone, stress-induced 3′ flap–based Okazaki fragment maturation supports cell survival
HAITAO SUN, ZHAONING LU, AMANPREET SINGH, YAJING ZHOU, ERIC ZHENG, MIAN ZHOU, JINHUI WANG, XIWEI WU, ZUNSONG HU, ZHAOHUI GU, JUDITH L. CAMPBELL, LI ZHENG, AND BINGHUI SHEN
SCIENCE 2 Dec 2021,Vol 374, Issue 6572 pp. 1252-1258
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07-Dec-2021 11:48
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Chromatin loading of MCM hexamers is associated with di-/tri-methylation of histone H4K20 toward S phase entry
Yoko Hayashi-Takanaka, Yuichiro Hayashi, Yasuhiro Hirano, Atsuko Miyawaki-Kuwakado, Yasuyuki Ohkawa, Chikashi Obuse, Hiroshi Kimura, Tokuko Haraguchi, Yasushi Hiraoka
Nucleic Acids Research, Volume 49, Issue 21, 2 December 2021, Pages 12152–12166
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07-Dec-2021 11:46
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The human telomeric proteome during telomere replication
Chih-Yi Gabriela Lin, Anna Christina Näger, Thomas Lunardi, Aleksandra Vančevska, Gérald Lossaint, Joachim Lingner
Nucleic Acids Research, Volume 49, Issue 21, 2 December 2021, Pages 12119–12135
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07-Dec-2021 11:45
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Structure of a human replisome shows the organisation and interactions of a DNA replication machine
Morgan L Jones, Yasemin Baris, Martin R G Taylor, Joseph T P Yeeles
EMBO J (2021)40:e108819