Welcome to the Interactive Section of the site. Here we will be posting papers and other replication news. Please feel free to add your comments to any of the postings here.

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A Substitution in the Fingers Domain of DNA Polymerase {delta} Reduces Fidelity by Altering Nucleotide Discrimination in the Catalytic Site Marc J. Prindle, Michael W. Schmitt, Fabio Parmeggiani, and Lawrence A. Loeb J. Biol. Chem. 2013 288: 5572-5580.
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Chromatin-dependent and -independent regulation of DNA replication origin activation in budding yeast Marko Lõoke, Kersti Kristjuhan, Signe Värv & Arnold Kristjuhan EMBO reports (2013), 14,191 – 198
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Translocation and Stability of Replicative DNA Helicases upon Encountering DNA-Protein Cross-links Toshiaki Nakano, Mayumi Miyamoto-Matsubara, Mahmoud I. Shoulkamy, Amir M. H. Salem, Seung Pil Pack, Yukio Ishimi, and Hiroshi Ide J. Biol. Chem. 2013 288: 4649-4658.
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Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases Won-Ho Cho, Young-Hoon Kang, Yun-Young An, Inger Tappin, Jerard Hurwitz, and Joon-Kyu Lee, PNAS February 12, 2013 vol. 110 no. 7 2523-2527
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Identification of RNF8 as a Ubiquitin Ligase Involved in Targeting the p12 Subunit of DNA Polymerase {delta} for Degradation in Response to DNA Damage Sufang Zhang, Yajing Zhou, Ali Sarkeshik, John R. Yates III, Timothy M. Thomson, Zhongtao Zhang, Ernest Y. C. Lee and Marietta Y. W. T. Lee J. Biol. Chem. 2013 288: 2951.
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Identification of Early Replicating Fragile Sites that Contribute to Genome Instability Jacqueline H. Barlow, Robert B. Faryabi, Elsa Callén, Nancy Wong, Amy Malhowski, Hua Tang Chen, Gustavo Gutierrez-Cruz, Hong-Wei Sun, Peter McKinnon, George Wright, Rafael Casellas, Davide F. Robbiani, Louis Staudt, Oscar Fernandez-Capetillo, André Nussenzweig Cell, Volume 152, Issue 3, 620-632, 24 January 2013
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