Mcm9
Related to Mcm2-7 family but apparently in distinct complex and much less abundant. Suggested involvement in initiation step of DNA replication. Only present in vertebrates.
Orthologues |
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Molecular weight |
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Biochemical properties
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Xl • Possible role in mcm 2-8 loading/ controlling cdt1:geminin ratio (1) |
Motifs |
Xl • n terminus has high homologyto MCM 2-8 (1) |
Interactions |
Xl • cdt1 and geminin ( low levels) (1)
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Modifications |
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Structure |
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Cellular location and expression |
Mammals
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Other comments |
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Revised by |
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Last edited |
13 July 09 |
1. Lutzmann,M. and Mechali,M. (2008) MCM9 binds Cdt1 and is required for the assembly of prereplication complexes. Mol Cell 31, 190-200.